1 Infectious Diseases Unit, Hospital Dona Estefânia, Lisboa, Portugal,
2 Instituto de Microbiologia, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal
Online International Journal of Microbiology Research Volume 1, Issue 2, pp. 20-24; March, 2013
http://www.onlineresearchjournals.org/OIJMR
Twenty-one children with community acquired Staphylococcus aureus osteoarticular infections were analyzed (2005-2008). One isolate was methicillin resistant S. aureus, presented spa type t008, a unique pulsed-field gel electrophoretic profile and was associated with pyomyositis. Two Panton-Valentine leukocidin positive isolates presented spa types t665 and t1848 and similar pulsed-field gel electrophoretic profiles. The outcomes were independent of methicillin resistance or Panton-Valentine leukocidin positivity. methicillin resistant S. aureus isolates showed diverse genetic lineages, similar to methicillin susceptible clones described in Europe, with spa types t002, t012, t015, t127, t008. Our data suggest that methicillin resistant S. aureus and Panton-Valentine leukocidin are not major factors influencing the outcome of these infections in Portugal.
Key words: Staphylococcus aureus, children, Panton-Valentine leukocidin, MRSA, Musculoskeletal infections.