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2023

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Factors associated with health-related quality of life changes in survivors to pediatric intensive care

Francisco Cunha1; Teresa Mota1; ArmandoTeixeira-Pinto2; Leonor Carvalho3; João Estrada4; António Marques4; Altamiro Costa-Pereira2; Luís Almeida-Santos1

1 Unidade de Cuidados Intensivos Pediátricos, UAG-MC Hospital S. João, Porto, Portugal
2 Departamento das Ciências da Informação e Decisão em Saúde, CINTESIS, Faculdade de Medicina, Universidade do, Porto, Portugal
3  Hospital Pediátrico Coimbra, Coimbra, Portugal
4  Unidade de Cuidados Intensivos Pediátricos, Hospital D. Estefânia, Lisboa, Portugal

- Revista Pediatric Critical Care Medicine, January 2013; volume 14, number 1 (Artigo)

OBJECTIVE: To determine predictors of change in the health-related quality of life in survivors to pediatric intensive care, based on preadmission health status, demographic characteristics, and physiological variables.

DESIGN: Prospective evaluation of health-related quality of life at PICU admission and after 6 months.

SETTING: Three PICUs at tertiary hospitals. PATIENTS:: Children aged ≥6 yrs admitted to the PICUs between May 2002 and June 2004.

INTERVENTIONS: Health Utilities Index Mark 3 questionnaire was administered to a child proxy by direct interview at admission and by telephone interview at follow-up.

MEASUREMENTS AND MAIN RESULTS:From the 517 eligible admissions, 44 (8.5%) children died in the PICU and 252 had a follow-up assessment. From a list of 115 analyzed variables, 29 (25%) and 30 (26%) were selected (p < .10) for a multivariable model predicting improvement and deterioration of the health-related quality of life, respectively. In the final models, only mechanical ventilation, preadmission global score of Health Utilities Index Mark 3, and preadmission Health Utilities Index Mark 3 pain attribute were associated with improvement; and main diagnostic group, preadmission Health Utilities Index Mark 3 emotion attribute, and preadmission Health Utilities Index Mark 3 pain attribute were associated with deterioration in the health-related quality of life.

CONCLUSIONS:The most common variables used to compute probability of death algorithms were not capable of predicting health-related quality of life in survivors to pediatric intensive care. The preadmission health-related quality of life and trauma admissions are important variables to predict change in the health-related quality of life of children surviving to pediatric intensive care.

Copyright © 2013 by the Society of Critical Care Medicine and the World.