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Patch testing in a case of eslicarbazepine and carbamazepine induced cutaneous reaction

Elena Finelli1; Pedro Custódio1; Oksana Porovska2; Sara Prates1; Paula Leiria-Pinto1

1 - Immunoallergology Department, Dona Estefânia Hospital, Centro Hospitalar Lisboa Central, Lisbon, Portugal.
2 - Occupational Health Department, São José Hospital, Centro Hospitalar Lisboa Central, Lisbon, Portugal.

Artigo publicado em Eur Ann Allergy Clin Immunol Vol 50, N 5, 229-231, 2018

Resumo: Anticonvulsants are among the drugs most commonly involved in cutaneous adverse drug reactions (CADRs). Eslicarbazepine is a new anti-epileptic drug, chemically related to carbamazepine but with a more favorable safety profile. We report the clinical case of a woman who developed a skin rash on day 10 of eslicarbazepine with further exacerbation with eosinophilia on day 2 of carbamazepine. Epicutaneous tests were positive with eslicarbazepine.

Palavras Chave: anticonvulsant drugs; drug allergy; epicutaneous tests; eslicarbazepine; skin rash