Serviço de Oftalmologia, Centro Hospitalar de Lisboa Central
- Comunicação oral - 44th Annual Meeting – European Paedriatic Ophthalmological Society, Budapeste , Setembro 2018
Purpose: Analyse peripapillary retinal nerve fiber layer (ppRNFL) using SD-OCT, as well as vascular density (VD) of the peripapillary vascular network (PVN) – OCT-A, between children with an increased cup/disc (C/D) ratio and normal ratio.
Methods: Non-randomized cross-sectional study of a sample of 28 eyes with an increased C/D ratio (group 1) and 28 eyes with a normal ratio (group 2), age and gender matched. Patients were characterized for cycloplegic spherical equivalent (cSE), intraocular pressure (IOP), C/D ratio and were evaluated for ppRNFL, macular thickness and PCN using SD-OCT and OCT-A. VD was obtained by AngioTool software.
Results: There was a significant decrease in the overall thickness of ppRNFL (p=0,006), as well as on the upper temporal (p=0,013), upper nasal (p<0,001) and nasal (p=0,013) quadrants in group 1, compared to group 2. Macular thickness in the external upper and nasal sector was also decreased in group 1. Children in this group had a significantly lower VD of those in group 2 (p<0,001). Unlike cSE (p=0,003), a significant difference in IOP between the two groups was not seen (p=0,315).
Conclusions: The observed differences make us question if optical discs with an increased C/D ratio are really healthy and show the significance of using OCT and OCT-A as screening methods in these children. Vascular density changes although potentially relevant, requires greater validation in order to guarantee reproducibility.
Palavras-chave: cup/disc ratio, pediatrics, OCT, OCT-A, glaucoma