1 – Neonatal Intensive Care Unit, Hospital Dona Estefânia, Centro Hospitalar de Lisboa Central, E.P.E.;
2 – Faculdade de Ciências Médicas, Universidade Nova de Lisboa;
3 – Pediatric Surgery Department, Hospital Dona Estefânia, Centro Hospitalar de Lisboa Central, E.P.E.
- Jornadas de Secção de Neonatologia da SPP 2012.10-12/05. Braga (Comunicação oral).
- Prémio Melhor Comunicação Oral. Jornadas de Secção de Neonatologia da SPP 2012.10-12/05.
- 3th UENPS Meeting 2012. 14-17/11. Porto (Comunicação oral).
- Sala de Conferências do HDE, 29 de Maio de 2012 (Apresentação).
Aim: To assess outcomes of NEC in a tertiary referral neonatal intensive care unit.
Methods and Patients: Observational study, historical cohorts. Four cohorts of patients were enrolled over 22 years, divided in 4 periods: 1990-1994 (A), 1997-2000 (B), 2001-2004 (C) and 2005-2011 (D). Data were gathered from a published paper (A), free communications (B and C) and newly studied (D). NEC grade I was excluded (n=52). Gestational age (GA), birth weight (BW), birth place, Bell´s modified classification stages, surgical intervention, length of stay (LOS), mortality, lethality and sequelae were studied.
Conclusions: Mortality and lethality rates have decreased over the 22 years period. As a consequence higher rates of complications and sequelae were found. These findings ascertain the severity of the disease.
Key-Words: Necrotizing enterocolitis, newborn, lethality.