Jornadas Nacionais de Neonatologia. Comunicação oral
Resumo:
Point-prevalence surveys are easy tools to assess prevalence of antibiotics use.
Aim: To assess the use of antibiotics in Portuguese neonatal Units.
Methods and patients: The surveillance occurred in one day, 2015, May(27th or 28th). The inquiry was sent online to 57 intermediate and intensive care neonatal units. All newborn infants in the unit on the day of the study had to be enrolled.
Results: Twenty three units delivered a complete answer: 3 placed in private hospitals, one in a public hospital with private running and 19 in public hospitals accounting for 106 intensive care beds and 221 intermediate care beds. Sixteen units admitted patients <1000g and 17<32 weeks; 15 had long lasting ventilation. The query covered 211 patients - 72 in intensive care and 139 in intermediate care. Fifty seven patients (27,3%) were under antibiotics (AB) because of perinatal infectious risk (n=14, 24.6% of patients on AB); early-onset infection (n=13 - 22.8%); late-onset infection (n=25, 39.3%); community-acquired infection (n=2); prophylaxis (n=3). Out of these 3, empiric prescription occurred in 44 patients and 10 following bacterial sensitivity. Three patients had no blood culture, in 2 it was contaminated, in 10 it was on going; 42 patients had the result already known: 32 were negative, 10 grew bacteria: 5CoNS, 1Kl spp, 1St. aureus, 1Streptococcus spp,1Listeria monocytogenes, 1Candida lusitanea. The most frequent association was ampicillin+gentamicin (27patients-47.4%), followed by vancomycin with: gentamicin(8 patients),cefotaxime(3 patients),amikacin(5 patients). Mean medication days-9(2-28).
Conclusion: The prevalence of patients on antibiotics was low; carbapenems and third generation cefalosporins were rare. Some associations deserve attention.
Palavras-Chave: Antibiotic prescription, Neonatal Units, Newborn infants, Point Prevalence Surveys